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maestro pro multi-well microelectrode array (mea) system  (Axion BioSystems)

 
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    Structured Review

    Axion BioSystems maestro pro multi-well microelectrode array (mea) system
    A: A scheme of Neural <t>microelectrode</t> array experiment. Neuronal cells are cultured and then infected with AAV virus. Neural microelectrode array <t>(MEA)</t> devices were used to detect infected neurons, and the potential measured with MEA is called the local field potential (LFP). B-F: Overexpression of the mutant allele of CRTC2 leads to significant increase of number of spikes (B), mean firing rate (C), burst during per second (s) (D), number of spikes per burst (E) compared to wildtype. However, no significant differences were observed between burst frequency (F) and number of burst (G). H-J: Typical mEPSC recordings of hippocampal neurons treated with PBS, CRTC2 WT, and CRTC2 mutation. In (H), sample traces of mEPSC recordings are illustrated. Quantitative analyses of mEPSC frequency and amplitude are presented in (I) and (J), respectively. Scale bar: 10pA, 2s. mEPSC: miniature excitatory postsynaptic current. *: P -value < 0.05, **: P -value < 0.01, ***: P -value < 0.001. ns, not significant.
    Maestro Pro Multi Well Microelectrode Array (Mea) System, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/maestro+pro+multi-well+microelectrode+array+%28mea%29+system/med_rxiv__2024__06__11__24308522-135-14-21?v=Axion+BioSystems
    Average 90 stars, based on 1 article reviews
    maestro pro multi-well microelectrode array (mea) system - by Bioz Stars, 2026-08
    90/100 stars

    Images

    1) Product Images from "Exome Sequencing of 963 Chinese Families Identifies Novel Epilepsy Candidate Genes"

    Article Title: Exome Sequencing of 963 Chinese Families Identifies Novel Epilepsy Candidate Genes

    Journal: medRxiv

    doi: 10.1101/2024.06.11.24308522

    A: A scheme of Neural microelectrode array experiment. Neuronal cells are cultured and then infected with AAV virus. Neural microelectrode array (MEA) devices were used to detect infected neurons, and the potential measured with MEA is called the local field potential (LFP). B-F: Overexpression of the mutant allele of CRTC2 leads to significant increase of number of spikes (B), mean firing rate (C), burst during per second (s) (D), number of spikes per burst (E) compared to wildtype. However, no significant differences were observed between burst frequency (F) and number of burst (G). H-J: Typical mEPSC recordings of hippocampal neurons treated with PBS, CRTC2 WT, and CRTC2 mutation. In (H), sample traces of mEPSC recordings are illustrated. Quantitative analyses of mEPSC frequency and amplitude are presented in (I) and (J), respectively. Scale bar: 10pA, 2s. mEPSC: miniature excitatory postsynaptic current. *: P -value < 0.05, **: P -value < 0.01, ***: P -value < 0.001. ns, not significant.
    Figure Legend Snippet: A: A scheme of Neural microelectrode array experiment. Neuronal cells are cultured and then infected with AAV virus. Neural microelectrode array (MEA) devices were used to detect infected neurons, and the potential measured with MEA is called the local field potential (LFP). B-F: Overexpression of the mutant allele of CRTC2 leads to significant increase of number of spikes (B), mean firing rate (C), burst during per second (s) (D), number of spikes per burst (E) compared to wildtype. However, no significant differences were observed between burst frequency (F) and number of burst (G). H-J: Typical mEPSC recordings of hippocampal neurons treated with PBS, CRTC2 WT, and CRTC2 mutation. In (H), sample traces of mEPSC recordings are illustrated. Quantitative analyses of mEPSC frequency and amplitude are presented in (I) and (J), respectively. Scale bar: 10pA, 2s. mEPSC: miniature excitatory postsynaptic current. *: P -value < 0.05, **: P -value < 0.01, ***: P -value < 0.001. ns, not significant.

    Techniques Used: Microelectrode Array, Cell Culture, Infection, Virus, Over Expression, Mutagenesis



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    Axion BioSystems maestro pro multi-well microelectrode array (mea) system
    A: A scheme of Neural <t>microelectrode</t> array experiment. Neuronal cells are cultured and then infected with AAV virus. Neural microelectrode array <t>(MEA)</t> devices were used to detect infected neurons, and the potential measured with MEA is called the local field potential (LFP). B-F: Overexpression of the mutant allele of CRTC2 leads to significant increase of number of spikes (B), mean firing rate (C), burst during per second (s) (D), number of spikes per burst (E) compared to wildtype. However, no significant differences were observed between burst frequency (F) and number of burst (G). H-J: Typical mEPSC recordings of hippocampal neurons treated with PBS, CRTC2 WT, and CRTC2 mutation. In (H), sample traces of mEPSC recordings are illustrated. Quantitative analyses of mEPSC frequency and amplitude are presented in (I) and (J), respectively. Scale bar: 10pA, 2s. mEPSC: miniature excitatory postsynaptic current. *: P -value < 0.05, **: P -value < 0.01, ***: P -value < 0.001. ns, not significant.
    Maestro Pro Multi Well Microelectrode Array (Mea) System, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/maestro+pro+multi-well+microelectrode+array+%28mea%29+system/med_rxiv__2024__06__11__24308522-135-14-21?v=Axion+BioSystems
    Average 90 stars, based on 1 article reviews
    maestro pro multi-well microelectrode array (mea) system - by Bioz Stars, 2026-08
    90/100 stars
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    A: A scheme of Neural microelectrode array experiment. Neuronal cells are cultured and then infected with AAV virus. Neural microelectrode array (MEA) devices were used to detect infected neurons, and the potential measured with MEA is called the local field potential (LFP). B-F: Overexpression of the mutant allele of CRTC2 leads to significant increase of number of spikes (B), mean firing rate (C), burst during per second (s) (D), number of spikes per burst (E) compared to wildtype. However, no significant differences were observed between burst frequency (F) and number of burst (G). H-J: Typical mEPSC recordings of hippocampal neurons treated with PBS, CRTC2 WT, and CRTC2 mutation. In (H), sample traces of mEPSC recordings are illustrated. Quantitative analyses of mEPSC frequency and amplitude are presented in (I) and (J), respectively. Scale bar: 10pA, 2s. mEPSC: miniature excitatory postsynaptic current. *: P -value < 0.05, **: P -value < 0.01, ***: P -value < 0.001. ns, not significant.

    Journal: medRxiv

    Article Title: Exome Sequencing of 963 Chinese Families Identifies Novel Epilepsy Candidate Genes

    doi: 10.1101/2024.06.11.24308522

    Figure Lengend Snippet: A: A scheme of Neural microelectrode array experiment. Neuronal cells are cultured and then infected with AAV virus. Neural microelectrode array (MEA) devices were used to detect infected neurons, and the potential measured with MEA is called the local field potential (LFP). B-F: Overexpression of the mutant allele of CRTC2 leads to significant increase of number of spikes (B), mean firing rate (C), burst during per second (s) (D), number of spikes per burst (E) compared to wildtype. However, no significant differences were observed between burst frequency (F) and number of burst (G). H-J: Typical mEPSC recordings of hippocampal neurons treated with PBS, CRTC2 WT, and CRTC2 mutation. In (H), sample traces of mEPSC recordings are illustrated. Quantitative analyses of mEPSC frequency and amplitude are presented in (I) and (J), respectively. Scale bar: 10pA, 2s. mEPSC: miniature excitatory postsynaptic current. *: P -value < 0.05, **: P -value < 0.01, ***: P -value < 0.001. ns, not significant.

    Article Snippet: To further investigate functional connectivity across a range of temporal scales, we utilized a Maestro Pro multi-well microelectrode array (MEA) system (Axion BioSystems).

    Techniques: Microelectrode Array, Cell Culture, Infection, Virus, Over Expression, Mutagenesis