maestro pro multi-well microelectrode array (mea) system (Axion BioSystems)
Structured Review

Maestro Pro Multi Well Microelectrode Array (Mea) System, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/maestro+pro+multi-well+microelectrode+array+%28mea%29+system/med_rxiv__2024__06__11__24308522-135-14-21?v=Axion+BioSystems
Average 90 stars, based on 1 article reviews
Images
1) Product Images from "Exome Sequencing of 963 Chinese Families Identifies Novel Epilepsy Candidate Genes"
Article Title: Exome Sequencing of 963 Chinese Families Identifies Novel Epilepsy Candidate Genes
Journal: medRxiv
doi: 10.1101/2024.06.11.24308522
Figure Legend Snippet: A: A scheme of Neural microelectrode array experiment. Neuronal cells are cultured and then infected with AAV virus. Neural microelectrode array (MEA) devices were used to detect infected neurons, and the potential measured with MEA is called the local field potential (LFP). B-F: Overexpression of the mutant allele of CRTC2 leads to significant increase of number of spikes (B), mean firing rate (C), burst during per second (s) (D), number of spikes per burst (E) compared to wildtype. However, no significant differences were observed between burst frequency (F) and number of burst (G). H-J: Typical mEPSC recordings of hippocampal neurons treated with PBS, CRTC2 WT, and CRTC2 mutation. In (H), sample traces of mEPSC recordings are illustrated. Quantitative analyses of mEPSC frequency and amplitude are presented in (I) and (J), respectively. Scale bar: 10pA, 2s. mEPSC: miniature excitatory postsynaptic current. *: P -value < 0.05, **: P -value < 0.01, ***: P -value < 0.001. ns, not significant.
Techniques Used: Microelectrode Array, Cell Culture, Infection, Virus, Over Expression, Mutagenesis